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Science, Sensory Experience, and the GLP-1 Effect Impact Innovation | State of the Supplement Industry

Consumers want evidence that what they take works and are becoming more discerning about ingredient quality, bioavailability, and efficacy.

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By: Catherine Nardone

VP Marketing, Concordix (Vitux)

Photo: peopleimages.com | AdobeStock

\As part of Nutraceuticals World’s 2026 State of the Industry review, Catherine Nardone, VP Marketing, Concordix (Vitux) explores how evolving health needs and shifting consumer expectations are driving innovation in supplement formulation and delivery.


Over the past year, the supplement landscape has been influenced by the growing use of GLP-1 therapies for weight management and the related conversations about nutrition and gut health. For users, reduced appetite and changes in digestion have created opportunities for supplements that support nutrient intake, metabolic function, and microbiome balance.

Brands have responded with formulations designed to maintain wellness and provide scientifically informed support for those navigating appetite changes and dietary adjustments — trends we expect to continue as GLP-1 therapies reach more consumers in 2026.

Gut health continues to evolve as a category. Beyond digestive comfort, the gut-brain axis has become a major focus, with research showing that the microbiome can influence mood, cognition, and overall well-being. Over the past year, we’ve seen innovation in supplements containing prebiotics, probiotics, and postbiotics that support gut function while promoting mental wellness.

As consumers increasingly recognize that overall health includes how they feel mentally and emotionally, demand for products supporting mental and emotional well-being is expected to continue growing, with vitamins, minerals, botanicals, and biotics increasingly incorporated into formulations to support overall balance.

“The momentum in advanced delivery, bioavailability, and consumer-centric innovation signals a defining era for the supplement industry — one in which science and sensorial experience are equally prioritized.”

Gen Z and Millennial consumers are embracing supplements for preventive health, while Boomers are using them to support longevity and vitality. Across demographics, there is a growing emphasis on clinically validated products — consumers want evidence that what they take works and are becoming more discerning about ingredient quality, bioavailability, and efficacy.

Clean label and traceability remain top priorities. People want to know where ingredients come from, how products are made, and what is in the final formula. Minimal excipients, transparent sourcing, and Western or GMP-certified manufacturing are increasingly viewed as signals of quality and trust.

Experience and adherence are now central to supplement innovation. Consumers want products that are not just tolerable but genuinely enjoyable to take — products that deliver measurable benefits, fit seamlessly into daily routines, and avoid unnecessary ingredients such as added sugar.

Brands that combine clinical efficacy, appealing formats, and transparency are capturing attention and loyalty, and we anticipate these expectations will continue to shape product development and innovation in 2026. The momentum in advanced delivery, bioavailability, and consumer-centric innovation signals a defining era for the supplement industry — one in which science and sensorial experience are equally prioritized.

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