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The new product, complete biotic, features a three-in-one, frosted orange-flavored powdered formula that can be poured directly on the tongue.
July 1, 2025
By: Mike Montemarano
Associate Editor, Nutraceuticals World
Thorne recently launched Complete Biotic, a three-in-one formula containing a prebiotic, probiotic, and postbiotic formulated to benefit bowel regularity, stool consistency, intestinal comfort, and growth of beneficial bacteria.
The product comes in a frosted orange-flavored powder format, which can be poured directly on the tongue, and it dissolves rapidly with no water required. It is suitable for both adults and children over the age of four.
According to Thorne, many benefits will be noticed over time when taking the probiotic.
After two weeks, it helps support normal stool consistency in people with occasional constipation or diarrhea. After a month of supplementation, expect a better balance of “good” bacteria, improved minor intestinal cramping, and support for healthy cholesterol levels. After two months, the supplement may support GI immune function in children. After three months, the formulation may improve overall quality of life measures, stool consistency, and emotional wellness in individuals with occasional GI upset.
The prebiotic in the formula is PreforPro, a clinically-studied bacteriophage that targets undesirable bacteria in the gut to create space for health-promoting bacteria to flourish. The probiotic in the formula is a Bacillus subtilis strain to promote GI comfort, regularity, and other measures of a healthy microbiome. Lastly, the postbiotic is a heat-treated Bifidobacterium longum, one of the most prevalent species in the GI tract, to support immune function.
“What excites us most about Complete Biotic is that it’s one of the first comprehensive gut health products that encompasses pre-, pro-, and postbiotics in a single offering,” said Ken Rowe, chief research and development officer at Thorne. “Consumers are becoming more conscious of their gut health each day, for good reason, yet so many don’t know where to start or even what the difference between a pre-, pro-, or postbiotic is. In addition, Complete Biotic provides a novel prebiotic as a non-fiber bacteriophage that supports the growth of beneficial bacteria while discouraging those that are not supportive to a healthy gut. We wanted to make it as easy as possible for our customers to support a healthy gut with clinically studied ingredients that are known to work well together and provide extensive microbiome support.”
“Complete Biotic is Thorne’s first fast-melt powder in single-serve packaging that doesn’t require any water and can be poured directly on the tongue and swallowed,” Rowe continued. “It has a smooth mouth feel, comes in a Frosted Orange flavor, and is convenient for consumers as it can be taken anywhere, whether traveling, at home, or on the go. We’ve continued to see a rise in demand for on-the-go options to help individuals maintain a consistent supplement routine wherever they are.”
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