Research

Citicoline Linked to Cognitive Benefits in Middle-Aged Adults: Study

The new findings on Kyowa Hakko’s Cognizin Citicoline were presented at the Symposium on Nutrition for the Aging Brain by ILSI Europe.

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By: Mike Montemarano

Associate Editor, Nutraceuticals World

Photo: Farnkot Architect | Adobe Stock

Ingredient supplier Kyowa Hakko recently presented new findings from a clinical study that provide new evidence that Cognizin Citicoline can support measures of cognitive performance in healthy, middle-aged adults. The findings were presented in the Fifth Symposium on Nutrition for the Aging Brain hosted by ILSI Europe earlier this month in Chania, Greece.

In a presentation, “Unlocking Brain Health: Evaluating the Role of Cognizin Citicoline in Cognitive Function,” Danielle Citrolo, PharmD, vice president of scientific and regulatory affairs, and Eri Nakazaki, PhD, manager in the health science department at Kirin Holdings, discussed the clinical research backing Cognizin’s role in brian health across age groups, and particularly in aging populations. The presentation reviewed key outcomes from randomized controlled trials, neuroimaging studies, and behavioral assessments.

Additionally, Citrolo and Nakazaki presented a new study that found Congizin supplementation was associated with improvements in sustained reaction time; cognitive performance in the domains of alertness, processing speed, and cognitive stamina; and rapid visual information processing (RVIP) reaction time, according to the company.

The presenters also discussed insights into the ingredient’s mechanism of action, including its roles in phospholipid metabolism, neurotransmitter synthesis, and mitochondrial function.

“Cognizin is backed by decades of clinical and preclinical research,” said Citrolo. “We’re proud to share our latest findings with the global scientific community and continue contributing to the evidence base for nutrition and cognitive health.”

“Cognizin represents a science-driven solution to support brain health at any age,” said Nakazaki. “Our findings reinforce the value of Cognizin as a nutritional intervention that aligns with the goals of healthy cognitive aging. Through both our oral presentation and poster, we aimed to demonstrate how Cognizine contributes meaningfully to the broader conversation on nutrition for the aging brain.”

Kyowa Hakko will also be participating at IFT First in Chicago from July 13-16, at booth S3037 where attendees can learn more about the research on Cognizin, the company’s branded glutathione ingredient, Setria, and more.

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