Algae Extract May Support Cognitive Function, Stress in Older Adults: Study

A microalgae extract produced by Microphyt was associated with improvements in measures of cognitive function and stress management in healthy, older adults, per a recent clinical study published in Frontiers in Aging.

The randomized, double-blind, placebo-controlled trial evaluated the effects of 6 months of daily supplementation with an ingredient called BrainPhyt in a population of 66 healthy adults between the ages of 55 and 75. BrainPhyt is an extract of Phaeodactylum tricornutum Mi136.a, rich in fucoxanthin, omega-3 fatty acids, and phycoprostanes. It is produced in France using MicroPhyt’s patented hydro-biomimetic technology.

“BrainPhyt offers a clinically-supported, natural solution for maintaining cognitive function during aging,” said Jonathan Maury, clinical research program manager at Microphyt and co-author of the study. “These results show real promise for improving memory and attention in healthy seniors, while also helping to balance inflammatory markers such as C-reactive protein.”

The study was conducted by Atlantia Clinical Trials. It utilized the COMPASS Assessment System to evaluate cognitive function. Blood samples were analyzed to assess biomarkers related to stress and inflammation. Mental health indicators, including measures of mood, sleep, and stress, were measured at baseline, week 12, and week 24 using standardized questionnaires.

Participants who took BrainPhyt had a 53% greater improvement in episodic memory; a 2.5-fold increase in measures of attention and vigilance including enhanced cognitive processing speed and accuracy; and reduced measures of stress and calmness compared to placebo.

The ingredient reduced C-reactive protein levels by 45%, and participants reported a significant reduction in perceived stress as measured by the Perceived Stress Scale.

Because inflammatory response and stress are associated with cognitive aging, BrainPhyt is formulated to break the self-perpetuating cycle in which inflammation, stress, and cognitive decline exacerbate one another, according to the company.

“These findings underscore BrainPhyt’s potential as a natural intervention to support cognitive health in the aging population,” said Christel Lemaire, marketing manager at MicroPhyt.

A previous 12-week study conducted by Texas A&M University yielded similar results, and found that supplementation with the ingredient resulted in improved measures of executive function, memory, and attention.