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Priome Oral Care, a strain of Lactiplantibacillus plantarum, appeared to reduce dental plaque accumulation over a placebo diet in 60 dogs.
August 13, 2025
By: Mike Montemarano
Associate Editor, Nutraceuticals World
A postbiotic marketed as Priome Oral Care by ADM was found to support the oral health of adult dogs when added to a dry kibble compared to placebo, a new clinical study found. The findings, published in Animals, show that the postbiotic supported markers of a healthy oral microbiome and contributed to reductions in dental plaque formation in a population of 60 dogs.
“Maintaining good oral hygiene in dogs is important to their overall wellness and it’s a growing concern among pet owners, yet regular toothbrushing can be challenging,” said Sophie Nixon, PhD, head of R&D clinical research for pet and animal wellbeing at ADM. “Our research highlights the potential for innovative postbiotic solutions to help support canine oral care and represents a promising step forward in identifying more convenient approaches to supporting oral health.”
In the study, 60 healthy adult dogs were given a dental cleaning and divided into three groups, which either received a dry kibble diet with a placebo, a low dose of Priome Oral Care, or a high dose of Priome Oral Care for 57 days. Researchers assessed dental plaque, gum health, bad breath, and tartar at intervals throughout the trial, and analyzed the oral microbiome.
Dogs receiving the high dose of the postbiotic saw a 10% reduction in dental plaque accumulation between day 29 and day 57. The low-dose group also had an overall trend toward reduced dental plaque formation compared to placebo. Additionally, the postbiotic may support overall oral health, according to the microbiome analysis.
“This study marks the first canine clinical trial to suggest the effects of PRIOME Oral Care and how it can reduce dental plaque formation in dogs and support their oral microbiome,” said Peter Jüsten, global vice president for health and wellness R&D at ADM. “This scientific publication is the culmination of many years of research and development work, spanning multiple ADM teams, sites and countries, and details the full process of strain identification, pre-clinical characterization and clinical substantiation. In addition, it contributes to an expanding body of scientific evidence supporting the role of postbiotics in reinforcing pet wellness.”
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