Research

BIO-CAT’s Xylanase Enzyme May Help Convert Fibers to Prebiotics During Digestion: Study

In a lab model of human digestion, the enzyme broke fiber-rich foods down into XOS.

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By: Mike Montemarano

Associate Editor, Nutraceuticals World

Photo: Grispb | Adobe Stock

BIO-CAT’s natural, non-GMO xylanase enzyme, when combined with fiber-rich foods like wheat bran, may help the body convert fiber into prebiotic compounds called XOS during digestion, a new study published in Food Chemistry found. XOS are able to feed short-chain fatty acid-producing gut bacteria to support better digestion, a healthy gut, and immune function.

“Most people want to eat healthier, but it’s not always easy to get enough fiber, especially around the holidays,” said Jim Farmar, PhD, principal scientist of the study. “This research shows that we may be able to make the fiber people already eat more beneficial for both the microbiome and for their health.”

The study used a well-established lab model of human digestion, mixing an endo-xylanase enzyme with wheat-based fiber. They found that the enzyme broke the fiber down into the smaller prebiotic compounds that are utilized by beneficial gut bacteria.

The next step, the authors noted, is conducting a human clinical study to see if the results observed in the lab model translate to direct human supplementation.

“As we head into a season of heavy meals and indulgence, it’s a great reminder that supporting your gut doesn’t have to be complicated,” said Farmar. “Small steps, like getting more fiber, can make a big difference.”

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