In this interview, Melissa Olivadoti, PhD, president of Assisi Consulting and advisor for Kaneka Nutrients, discussed the importance of ubiquinol supplementation for women as they age.

The active antioxidant form of CoQ10, ubiquinol plays a critical role in protecting cells from oxidative stress and supporting energy production. Because natural ubiquinol levels decline with age and cannot be restored through diet alone, supplementation may help women maintain healthy antioxidant defenses, particularly during perimenopause and menopause, when estrogen levels decrease.

Olivadoti also highlighted the role of ubiquinol in reproductive health, noting its importance for mitochondrial function and healthy egg cells during preconception. Since oocytes have especially high energy demands and are vulnerable to oxidative stress, supporting mitochondrial health with ubiquinol supplementation may help optimize egg quality for women trying to conceive.

Ubiquinol may also support cardiovascular health and healthy aging by promoting healthy mitochondria in heart cells, supporting blood vessel flexibility, and helping protect LDL cholesterol from oxidation. Menopausal women taking 200 mg of Kaneka Ubiquinol® daily for two months reported improvements in irritability, stress, sensitivity, and mood swings, suggesting wellness benefits during this stage of life.

Discussion Topics:

• The role of ubiquinol as a key antioxidant and why natural levels decline with age
• How oxidative stress and reduced estrogen levels impact women during perimenopause and menopause
• Ubiquinol’s role in mitochondrial health, egg quality, and preconception support
• Research on ubiquinol and cardiovascular health, including heart cell energy production and LDL oxidation
• Clinical findings on ubiquinol supplementation and benefits for menopausal women, including mood and stress support